Alex Iwobi scored twice as Nigeria fought back from 2-0 down against an Argentina side missing Lionel Messi to secure a stunning 4-2 friendly victory in Krasnodar.
Sergio Aguero scored his 36th international goal to move clear in third place on Argentina's all-time scoring list as Jorge Sampaoli's side looked set to prosper despite the absence of Messi, who had returned to Barcelona after featuring in the 1-0 win over Russia on Saturday.
Having drawn level with Hernan Crespo by scoring a late winner against the Russians, Aguero followed up his first international goal since June 2016 by tapping home Argentina's second to back up Ever Banega's free-kick opener.
Yet their comfortable cushion evaporated either side of the interval, with Kelechi Iheanacho inspiring a Nigeria fightback with a free-kick of his own in the closing stages of the first half.
Two goals in the space of three second-half minutes from Iwobi and Bryan Idowu swung the game further away from Argentina, with the former then slotting home a fourth to secure Nigeria just their second ever win over their South American opponents.
The astonishing turnaround came after Banega's 28th-minute free-kick gave Sampaoli's side a deserved lead - albeit they needed help from goalkeeper Daniel Akpeyi to break the deadlock.
After nudging the ball outside his own penalty area, a careless Akpeyi curiously allowed Aguero to quickly close the gap, forcing him to pick it up to prevent embarrassment.
He did not escape punishment for his error, however, as Banega curled the resulting set-piece opportunity into the net, Akpeyi opening up further space to target by taking an unnecessary step behind his wall.
Aguero added a second eight minutes later to move clear of Crespo, the striker tapping home Cristian Pavon's low cross from the right, and at that stage Argentina were coasting.
Nigeria had barely threatened in the first half but still managed to get back in the game, Iheanacho following Banega's example by scoring from a free-kick in the final minute of the first half.
FT: Argentina 2-4 Nigeria.— Super Eagles (@NGSuperEagles) November 14, 2017
We turned around a 2 goal deficit to beat Argentina.
The Krasnodar fans are giving our team a loud applause and standing ovation for an incredible performance#SoarSuperEagles.
The Leicester City striker's effort came after he had earlier left an impression on Nicolas Otamendi, catching his former Manchester City team-mate with an elbow.
Yet Iheanacho escaped with only a yellow card and, after halving the deficit, he heaped further pain on Argentina by setting up Nigeria's quick-fire double after the break.
Not content with a square pass from the right that allowed Iwobi to sweep home an equaliser, the 21-year-old forward played in the supporting Idowu to curl a right-footed effort beyond goalkeeper Agustin Marchesin.
Hit by a one-two combination, Argentina struggled to mount a response as they looked to get back on level terms in a game that had somehow escaped from their grasp.
With no Messi to inspire any late heroics, Iwobi wrapped up the victory for Nigeria, the Arsenal forward finishing with his left foot after swerving his way beyond Javier Mascherano.
|Villa determined to earn place in Spain´s World Cup squad|
|BREAKING NEWS: Walcott swaps Arsenal for Everton|
|Kohli bristles at selection questions|
|England forward Haskell handed four-week suspension|
|You even learn from Guardiola at home - Otamendi lauds Pep impact|
|Three-week ban for Bastareaud for alleged homophobic slur|
|IOC to consider joint Korean ice hockey team|
|Sri Lanka ODI woes drag on with Zimbabwe defeat|
|Batsmen let India down against South Africa - Kohli|
|Five fun facts as LeBron James chases 30K career points|
|Bastareaud named in France squad ahead of disciplinary hearing|
|Otamendi pens Man City deal to 2022|
|Neymar leads tributes to retiring Ronaldinho|
|Ronaldo must focus on playing - Zidane sidesteps exit talk|
|Dimitrov, Tsonga survive gruelling battles as Nadal cruises through|
|Carey ton sends Strikers back top of BBL|
|Zidane still an idol for James despite ´sad´ Madrid exit|
|Stoger will stay at Dortmund if ´everything fits´|
|Nadal backs move for financial parity but silent on boycott talk|
|Stokes available for England selection, set for NZ return|
|Bordeaux´s Malcom facing disciplinary action over social media video|
|Debutant Ngidi hurries SA to series win as India crumble in Centurion|
|Eddie Jones signs new England contract|
|Ronaldinho retires – The greatest Brazilians to play for Barcelona|
|England setting the benchmark in ODIs, says Warner|
|Federer would be unreal at any sport - Shapovalov|
|Athletic reward Williams with contract until 2025|
|Nadal too good for Mayer at Australian Open|
|Jones taking unlikely inspiration from City in United´s title pursuit|
|I had one foot out of the Australian Open – Wozniacki revels in fightback|
|Beware the nearly beaten in Melbourne – Wozniacki could match Kerber, Li|
|Rallying Tsonga outlasts Shapovalov in five-set epic|
|Wozniacki saves two match points in dramatic Aus Open comeback|
|Kostyuk, 15, ready to spend after Melbourne run|
|Thomas turns down Celtics´ video tribute|
|Moyes unaware of Chelsea interest in Carroll|
|Verdi wants Bologna stay amid Napoli links|
|Ronaldinho retires – A shining light of Brazil´s 2002 World Cup-winning team|
|Ronaldinho retires – a World Cup and Ballon d´Or among Brazil great´s prizes|
|Celtics great White dead at 71|
|World Cup glory and Bernabeu magic - Ronaldinho´s best moments for Barca and Brazil|
|Trust the Process – 76ers only behind Warriors and Cavs in merchandise sales|
|Ligue 1 Review: Balotelli at the double as Payet shines and Malcom toils|
|Pato still dreaming of World Cup selection|
|FA Cup Review: Iheanacho makes VAR history, kit confusion reigns|
|Wallaby saves wallaby: Farr-Jones in Sydney Harbour Bridge rescue mission|
|2016-17 UEFA Study: PSG, Man City drive record-breaking spending|
|Conte packing in homework as Chelsea games stack up|
|2016-17 UEFA Study: The headlines in transfers, wages and revenues|
|2016-17 UEFA Study: Manchester United record highest revenue but largest debt|
|Monaco stay perfect, Murcia overcome Oldenburg|
|Iheanacho scores English football´s first VAR goal|
|Materazzi not surprised by Coutinho transfer fee|
|Ronaldinho retires - Brazil and Barca great plans 2018 farewell|
|Jags RB Leonard Fournette uninjured in three-car accident|
|India revenge would heal Proteas´ scars - Elgar|
|Koziello swaps Nice for Cologne|
|Simeone ready to unleash Costa and Vitolo alongside Griezmann|
|Head coach Cooper to leave Stade Francais|
|Silverwood plays down talk of replacing Bayliss|
|Lambert ´never thought´ he would return to Premier League|
|Wenger ´very aggressive´ towards referee Dean, says FA report|
|Reported Arsenal target Malcom starts for Bordeaux vs Caen|
|Valverde not making big deal of Dembele´s latest Barca blow|
|Costly day for Kohli as Proteas close in on series win|
|Date set for Afghanistan´s maiden Test|
|Returning McIlroy ready to end winless run|
|In-form Short leaves coach Kirsten needing dental treatment|
|Arsenal will have a ´hard time´ signing Malcom|
|Ronaldo and Madrid nominated for Laureus awards|