Sergio Aguero will not play again for Manchester City this season and will now focus upon recovering in time for Argentina's World Cup campaign, his club manager Pep Guardiola has confirmed.
Aguero underwent keyhole surgery on his right knee in Barcelona earlier this week after he failed to fully recover from a heavy challenge by Ashley Young in City's 3-2 derby defeat against Manchester United.
United's shock 1-0 loss to West Brom last weekend meant City wrapped up the Premier League title with five matches to spare and Aguero, who was named in the PFA Team of the Year, will not feature again at the Etihad Stadium until 2018-19.
Asked whether the 29-year-old's season was over, Guardiola told a news conference: "Here, yeah. It is four or five weeks. Hopefully we are going to try for him to be ready for the World Cup.
"He is in Barcelona right now for the first part of the rehabilitation."
Muy feliz y orgulloso por integrar el Equipo del Año de la Premier League de la PFA Gracias #PFAawards! Y felicitaciones a mis compañeros!//I'm very happy and proud to be part of The PFA Premier League Team of the Year Thanks #PFAawards! Congratulations to my teammates! https://t.co/EMkYqUPjTa— Sergio Kun Aguero (@aguerosergiokun) April 18, 2018
Aguero's attention is now firmly fixed upon Argentina's World Cup opener against Iceland in Moscow on June 16.
Jorge Sampaoli has ample striking options at his disposal – Gonzalo Higuain and Paulo Dybala were left out of his squad for last month's friendlies against Italy and Spain – but City's all-time leading scorer had looked set to be a key part of their tilt for World Cup glory in an attack led by Lionel Messi.
However, Argentina's team doctor Homero D'Agostino said this week that he fears Aguero will struggle to be at peak fitness by the time Russia 2018 comes around.
"That a player has undergone an arthroscopy with 60 days to go before the World Cup is worrying," D'Agostino told Radio 10.
"The recovery process will require at least five weeks. When one has old injuries, the recovery process is not as fast as one would like it to be. It's never going to be less than three or four weeks, or even more.
"I imagine that he will not arrive 100 per cent fit with the limited time that is left before the World Cup. The anatomy is the anatomy. The injury is what it is. He can try but I don't think he will arrive 100 per cent.
"The important thing is to know what he had. The doctors would have tried to resolve the issue in a conservative manner, non-surgically, but they were unsuccessful. The arthroscopy is a process that you do when there are old injuries."
|DeGrom strikes out 12, Mets hit 5 homers in win over Yankees|
|Djokovic needs nine MPs as Murray crashes out|
|Murray unsure of US Open readiness after Cincinnati exit|
|Van Dijk: Alisson making difference at Liverpool|
|Johnson saves eight MPs but Djokovic prevails|
|Federer anxious ahead of Cincinnati comeback|
|Tevez relishing Messi reunion|
|Ronaldo arrival has taken Juve forward in Europe – Nedved|
|Serena steamrolls Gavrilova in Cincinnati return|
|Packers QB Rodgers doesn´t regret criticising team-mates|
|Indians OF Martin recovering from life-threatening bacterial infection|
|Shoulder injury sends Royals starter Duffy to DL|
|Yankees place Sabathia on DL with right knee inflammation|
|Aubameyang urges Emery to capitalise on his ´spark´ with Lacazette|
|Anderson can play until he´s 40, says Bayliss|
|Keita living childhood dream after securing Inter switch|
|49ers to sign veteran RB Alfred Morris, Kyle Shanahan says|
|Arnaiz leaves Barcelona for Leganes in €5m deal|
|Tottenham´s move to new stadium delayed|
|Roosters-bound Hall suffers ACL injury|
|Murray suffers Cincinnati defeat to Pouille|
|No Cech mate - Arsenal goalkeeper hits back at Bayer Leverkusen|
|Halep first to seal WTA Finals spot|
|Veteran Carmelo Anthony pens one-year Rockets deal|
|Runners and Ryders: Poulter closes in on Team Europe spot|
|Gameiro presented by Valencia after departing Atletico Madrid|
|World Cup winner Kimpembe extends PSG contract to 2023|
|AC Milan send Locatelli on loan to Sassuolo|
|South Africa´s Etzebeth set for return from injury|
|Rafinha ´very likely´ to stay at Barcelona|
|No dual Ryder Cup role should Woods make USA team, says Furyk|
|Inter complete Keita deal|
|David Silva announces retirement from international football|
|Modric in Real Madrid´s UEFA Super Cup squad amid Inter links|
|Neville hopes Shaw is on to something special after first United goal|
|Unchanged England waiting on Stokes verdict|
|Yates brothers to race Vuelta together|
|Kalinic explains why he rejected World Cup medal|
|Furyk excited to see Woods´ return to form|
|Liverpool ignoring media´s champions chat, says Van Dijk|
|Suspended Smith replaces Kohli as top-ranked Test batsman|
|Tiger fanfare inevitable but it´s time to recognise Koepka as the star he is|
|Dier: Tottenham will shut up transfer critics|
|Fernandes leaves West Ham for Fiorentina on loan|
|´No chance´ Willian would have stayed at Chelsea under Conte|
|Vettel confident he can catch Hamilton|
|Cane dismisses talk of All Blacks limiting haka|
|Zaha promises Palace commitment as contract talks continue|
|Real Madrid defender Odriozola to miss UEFA Super Cup|
|All Blacks wary of Pocock threat|
|Bayern Munich confirm no ligament damage for Alaba|
|Nicklaus hails Koepka´s great year after US PGA triumph|
|Keita ready to ´explode´ at Inter|
|Halep: Stephens makes me a better player|
|Manchester United loan Wilson to Aberdeen|
|Beale backs Hodge to start in Rugby Championship opener|
|Bakayoko arrives for AC Milan medical|
|Australia favourites for Rugby Championship opener, says Hansen|
|Muller hails Lewandowski: That´s why Bayern won´t let him go|
|Allegri eyes Champions League after watching Ronaldo score first Juventus goal|
|LaLiga 2018-19: Barcelona or Real Madrid - whose close-season transfers have been better?|
|Fekir almost certain to stay at Lyon, says Aulas|
|Tuchel unaware of PSG deal for Kehrer|
|MLS Review: Rooney´s heroics lift DC, Villa inspires NYC|
|Sale strikes out 12 in Red Sox´s win over Orioles|
|Scott buoyed by Bellerive display|
|Edmund, Mannarino win Cincinnati openers|
|WATCH: Rooney saves open goal before setting up last-gasp winner|
|Kovac praises three-goal Lewandowski but thanks Heynckes|
|Nadal withdraws from Cincinnati Masters|