Palmeiras booked their spot in the Copa Libertadores knockout rounds, while Nacional claimed their first win of the group stage on Wednesday.
Goals from Keno and Lucas Lima saw Palmeiras record a 2-0 victory over Boca Juniors in Buenos Aires.
Keno opened the scoring five minutes before half-time, heading in a Marcos Rocha cross from the right.
Brazil international Lucas Lima sealed the result with a 35-yard chip after Boca goalkeeper Agustin Rossi was left stranded having come to clear.
Palmeiras are top of Group Eight on 10 points, five clear of Boca.
In Group Six, Nacional recorded a much-needed 4-0 win over Real Garcilaso in Montevideo.
A 25-yard free-kick from Sebastian Rodriguez put the hosts ahead before they struck three times in the final 10 minutes.
Guzman Corujo headed in Nacional's second before Leandro Barcia and Gonzalo Bergessio sealed the victory.
Nacional climbed into second in the group on five points, four behind Santos and one clear of Estudiantes and Real Garcilaso.
In Group One, Monagas stunned Defensor Sporting 1-0, while Atletico Tucuman cruised past The Strongest 3-0 in Group Three.
Flamengo and Santa Fe played out a 0-0 draw in Bogota in Group Four.
|Halep hits back to torment Tsurenko|
|Raonic fails to break Djokovic stranglehold|
|Emery seeks more ´demanding´ Ozil|
|CAF Champions League Review: Wydad, Al Ahly & TP Mazembe qualify|
|Stephen Curry wants to finish his career with Warriors|
|Hazard among Europe´s best but can improve, says Sarri|
|Tigers boost top-two hopes, Giants close in on fourth|
|Birmingham City 0 Swansea City 0: Monk´s men held despite dominance|
|Inter taking legal action against Tebas over Modric transfer comments|
|Serie A transfer round-up: Zaza joins Torino, Parma sign Gervinho|
|Roma chief Pallotta makes light of De Laurentiis claim|
|Federer starts double-header by seeing off resilient Mayer|
|Ospina joins Napoli on loan from Arsenal|
|Klavan completes Cagliari switch|
|Djokovic holds out against Dimitrov as Raonic awaits|
|New dates confirmed for postponed Serie A fixtures|
|Halep breezes past Barty to set up Tsurenko clash on same day|
|Olesen unable to capitalise on strong start as Jamieson, Waring go clear|
|Hoffenheim tie Kramaric to four-year deal|
|Mina to miss Southampton clash while Gomes is ´weeks´ away|
|Barcelona coach Valverde dismisses Pogba speculation|
|Valverde not prioritising Champions League over defending Barcelona´s LaLiga title|
|Allegri thanks outgoing Juventus icon Marchisio|
|Pants display from Beef? Johnston forced into change of trousers in Sweden|
|Tour champion Thomas has Welsh velodrome named in his honour|
|Gloucester surprised and disappointed by RFU´s swift Cipriani charge|
|Storm skipper Smith´s back injury not ´too serious´|
|Spurs fixture switch doesn´t appeal to Guardiola|
|Brazil call up Andreas Pereira & Arthur but omit Man City stars|
|Mbappe returns to PSG squad, Kehrer set for debut|
|No Messi in Argentina squad as Simeone wins first call-up|
|England man Roy embarrassed by self-inflicted facial injury|
|Atletico Madrid fined for breaching third-party regulations|
|Cipriani charged by RFU after common assault conviction|
|No contact, no negotiation - Leonardo denies AC Milan deal for Milinkovic-Savic|
|Kovacic set for Chelsea debut against Arsenal|
|Fury´s father restrained as Wilder crashes Pianeta weigh-in|
|Kohli and Bumrah fit for win-or-bust Test|
|Stokes ready and desperate to help England, says Root|
|Salah, Mane and Firmino not in competition says Klopp|
|Darmian staying at Manchester United, says Mourinho|
|Guardiola cites fatigue as factor for stricken De Bruyne|
|Kovac approves Rudy departure from bloated Bayern midfield|
|Klopp insists no player leaves without his approval amid Klavan rumours|
|Real Madrid complain to FIFA over Inter´s alleged Modric approach|
|Mourinho ´has never been so happy´ with unsettled Pogba|
|Manly implode amid Barrett uncertainty, Storm´s Smith injured|
|Sarri certain Hazard is staying at Chelsea|
|Liverpool, Champions League, Manchester derby - The matches De Bruyne will miss due to injury|
|Campbell joins Frosinone from Arsenal on permanent deal|
|Schalke sign Lille´s Mendyl to end left-back hunt|
|Stokes back in England team as Curran drops out|
|Ronaldo doesn´t guarantee Juventus the title, warns Allegri|
|Tuchel keen to guide PSG star Mbappe after World Cup heroics|
|Yuri: I can see Neymar joining Real Madrid|
|Milan pounce for Castillejo as Bacca joins Villarreal permanently|
|De Bruyne to miss three months for Manchester City|
|Manchester City talent Arzani completes Celtic loan|
|I know how precious my career is, says regretful Cipriani|
|Paulo Bento named new South Korea coach|
|Milan complete Laxalt deal|
|Poyet suspended by Bordeaux after outburst against board|
|Tuchel will let Neymar and Cavani settle penalties themselves|
|Hooper: We´re ready, bring on the All Blacks!|
|Outstanding Australia deserve our respect - Read|
|Dragons´ Widdop set for Finals return|
|Jamshed found guilty of corruption and banned for 10 years|
|Bennett will not be sacked, insist Broncos|
|Marchisio leaves Juventus|
|The Breakdown: A statistical look at round one of the Rugby Championship|